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Description
Human Desmoglein 3, His tagProduct Specification Species Human Synonyms 130 kDa pemphigus vulgaris antigen (PVA), Cadherin family member 6, DSG3, CDHF6 Accession P32926 Amino Acid Sequence Protein sequence(Q29432, Arg54 Val380, with C 10*His)
Product Specification
| Species | Human |
| Synonyms | 130 kDa pemphigus vulgaris antigen (PVA), Cadherin family member 6, DSG3, CDHF6 |
| Accession | P32926 |
| Amino Acid Sequence | Protein sequence(Q29432, Arg54-Val380, with C-10*His) RGSNLTTHPLRNIKDLVYMGNITIGTPPQEFQVVFDTASSDLWVPSDFCTSPACSTHVRFRHLQSSTFRLTNKTFRITYGSGRMKGVVVHDTVRIGNLVSTDQPFGLSIEEYGFEGRIYDGVLGLNYPNISFSGAIPIFDKLKNQRAISEPVFAFYLSKDEREGSVVMFGGVDHRYYEGELNWVPLIQAGDWSVHMDRISIERKIIACSDGCKALVDTGTSDIVGPRRLVNNIHRLIGAIPRGSEHYVPCSEVNTLPSIVFTINGINYPVPGRAYILKDDRGRCYTTFQENRVSSSTETWYLGDVFLRLYFSVFDRGNDRIGLARAVGGGGSHHHHHHHHHH |
| Expression System | HEK293 |
| Molecular Weight | Theoretical:17.6kDa Actual:20-30kDa |
| Purity | ＞95% by SDS-PAGE |
| Endotoxin | <1EU/μg |
| Tag | His Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | Lyophilized from a 0.2 μm filtered solution of 0.2M PBS, 1mM EDTA, pH7.4. |
| Reconstitution | Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation. |
| Stability & Storage | 12 months from date of receipt, -20 to -70 °C as supplied. 6 months, -20 to -70 °C under sterile conditions after reconstitution. 1 week, 2 to 8 °C under sterile conditions after reconstitution. Please avoid repeated freeze-thaw cycles. |
Background
Desmoglein-3 is a protein that in humans is encoded by the DSG3 gene. In the skin epidermis Desmoglein-3 is expressed in the basal lower layers of the epidermis, and dominates in terms of expression on mucosal surfaces compared to Desmoglein-1. Desmoglein-3, along with Desmoglein-1, has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus vulgaris. The mucosal dominant form of pemphigus vulgaris only involves antibodies against Desmoglein-3 and causes mucosal erosions, but no skin lesions. Desmoglein-3 serves as a prognostic marker of Esophageal Squamous Cell Carcinoma (ESCC), and may even be involved in the progression of ESCC.
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4.1 ★★★★★
Based on 89 reviews
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Product Reviews
★★★★★ 4
A very erudite validation of alternative energy healing
Format: Paperback
I have not got very far in reading since I am reading in parallel Rosalyn Bruyere's "Wheels of Light", but so far find it more accessible than Ms Brennan's first book, "Hands of Light" and this is quite natural since I am not a scientist. But I can't help feeling that in many instances of alternative healing modalities, a personal experience of a natural gift of healing is being made to appear to the general public as a complex and costly necessity for effecting the healing that is a natural propensity of one's body if not hindered by pre-conditioning. Notwithstanding this, I like this book because is speaks to a personal experience of healing energy as subtle sensation/LIGHT which I see as merely awaiting universal acknowledgment that ALL is Light, appearances to the contrary to be shattered by such acknowledgment, and all advances in science that corroborate that fact is welcome.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on January 14, 2013
★★★★★ 5
A great resource for those on their own healing journey and others
Format: Kindle
It is said that energy medicine is the next frontier of medicine. This book helps to explain why. Barbara has decades of experience working with physics, counseling, high sense perception, as well as watching and assisting thousands of people manage their energy field for wellness.
Her first book "Hands of Light" is more like a technical manual (and fascinating). This book is written for all of us - on our own healing journey and how we can **empower our selves in our own health and well being**. How we view and assimilate western concepts of "medicine", medication, therapy and other interactions into our own self has more to do with health than the intervention alone.
It is also a great resource for healers, psychologists, medical professionals - anyone in a service profession aimed to assist others in their health and wellness. The concepts are powerful when practiced with intention and depth of management of our own field. We can help others by simply managing our own awareness, mindfulness and field.
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Reviewed in the United States on January 5, 2013
★★★★★ 5
The perfect companion to Hands of Light
Format: Paperback
I love Barbara Brennan's first book Hands of Light, which I read waaaaay back when it first came out! Could not put it down and it was the one that got me started on spiritual path and exploring healing practices such as Reiki, Jin Shin Jyutsu, IET and all the other energy healing modalities. Now I am reading Light Emerging and as her first book is, it's so informative. This one is focusing on personal healing, healer and patient interaction, relationships and energy interaction and how to create positive patterns, and more. I would love to go to the Barbara Brennan School of Healing one day but in the meantime these books will carry me through to learning about healing and express myself in a more loving & nurturing way for myself and for others. This book & her first book are a must for anyone interested in exploring these types of therapy and discovering their own built-in ability to heal with energy. Enjoy!
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 2, 2014
★★★★★ 5
Well written book. The author really explains EFT Tapping well. Detailed review...
Format: Kindle
Well, I must say that before reading this book, I was a doubting Thomas about EFT Tapping. Then I looked up eBooks about controlling pain naturally and rediscovered EFT Tapping method for relieving pain, anxiety, Stress and more. While I found lots of books here on Amazon (Kindle versions), what I needed was a MANUAL for EFT Tapping....You know, a basic yet effective HOW TO (Illustrated) book.
1) This is the exact book I was looking for, a how to book. No fluff, just helpful stuff.
2) So I read this book and then I tried the tapping how to do. She explained that tapping with one hand is best, I tied it and it worked.
3) This book is more of a beginner book, a starting g point. However I did some tapping (just started), and my shoulder pain went from a 8 to a 4 after the first try.
(I think this worked for me because when I stress, my right shoulder (old injury) hurts.
This book has been both inspiring and helpful for me personally, I intend to continue to refer to this book and keep on Tapping!
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Reviewed in the United States on June 30, 2017
★★★★★ 5
Fantastic Author!
Format: Kindle
I love this Tessa Cason’s work. EFT is such a wonderful technique to work through difficult things. Tessa is so clear in her writing about what this technique is about and how it works. She gives great explanations of EFT and how it works. Makes it easy to understand and use EFT for yourself. I highly recommend her books to people who are both new and those who are experienced with EFT.
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Reviewed in the United States on February 15, 2022
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